The role of ROS in exercise mediated WAT browning. Exercise causes oxidative stress in skeletal muscle and reduces the level of GSH. GSH provides electrons for glutathione peroxidase (GPXs), which eliminates H2O2. Reducing Figure 1 from The Emerging Role of Glutathione in Alzheimer's Disease Semantic Scholar Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Vaccinia related kinase 2 inhibition elicits vulnerability of glutathione metabolism in pancreatic cancer Cell Death & Disease
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