Blister Cell in G6PD Deficiency , Red Blood Cell with a clear vacuole like area on its membrane, resembling a blister., It usually results when splenic macrophages remove precipitated Heinz Glucose 6 Phosphate Dehydrogenase Deficiency Oncohema Key Figure, Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency. Diagram] StatPearls NCBI Bookshelf G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione (